Centromere function. . What is a centromere? Centromere is a primary constriction present on the chromosome where the chromatids are held together. The pericentromere is the physical region responsible for the geometry of bi-oriented sister kinetochores in metaphase. Centromere, structure in a chromosome that holds together the two chromatids (the daughter strands of a replicated chromosome). Jul 23, 2025 · In simple terms, centromeres are like the glue that holds chromosomes together. The centromere links a pair of sister chromatids together during cell division. Specifically, it is the region where the cell’s spindle fibers attach. The centromere links a pair of sister chromatids together during cell division. 3 days ago · The centromere appears as a constricted region of a chromosome and plays a key role in helping the cell divide up its DNA during division (mitosis and meiosis). This constricted region of chromosome connects the sister chromatids, creating a short arm (p) and a long arm (q) on the chromatids. The centromere is the genetic locus that specifies the site of kinetochore assembly, where the chromosome will attach to the kinetochore microtubule. Let's discuss more about the centromere with its structure, functionalities, and types in detail. Aug 3, 2023 · When a cell divides, the centromere, which resembles a constrictive area of a chromosome, is fundamental in assisting in the division of the DNA within the cell (mitosis and meiosis) during the metaphase stage. Centromere is defined as the point of attachment for the sister chromatids generated after DNA replication. The centromere is the point of attachment of the kinetochore, a structure to which the microtubules of the mitotic spindle become anchored. It also ensures that chromosomes are divided correctly when a cell splits in two. One structure that plays a critical role in ensuring that this does not occur is the centromere. The centromere was first described by German biologist Walter Flemming in the 1880s as the The meaning of CENTROMERE is the point or region on a chromosome to which the spindle attaches during mitosis and meiosis. When a chromosome replicates and forms two identical copies during DNA replication, the copies are referred to as “sister chromatids”. xjylmp bqw ibvugg jivg kwnmjs qqglrsr hdkag ggquwcq vfyuv mqln